How many Americans have a health problem and don’t know it?

Some of the most common health problems cause no symptoms for years. Here’s how many people have them, how many don’t know, and the simple tests that find them.

Updated October 2026 · Data: Centers for Disease Control and Prevention (CDC)
Quick answer

Tens of millions. 8 in 10 US adults with prediabetes don’t know they have it, and that’s about 92 million people. About 9 in 10 adults with chronic kidney disease don’t know. About 4 in 10 adults with high blood pressure haven’t been told they have it, and 11 million people have diabetes that hasn’t been diagnosed. Most of these can be found with a blood pressure check or a routine blood test.

8 in 10
adults with prediabetes don’t know it
9 in 10
adults with kidney disease don’t know it
4 in 10
adults with high blood pressure don’t know it
11.0M
people with diabetes that hasn’t been diagnosed
The short version
  • Feeling fine doesn’t mean you’re fine. These conditions usually cause no symptoms for years.
  • They’re common. Almost half of US adults have high blood pressure, and more than 2 in 5 have prediabetes.
  • They’re connected. Diabetes and high blood pressure are the two biggest causes of kidney disease.
  • Younger adults miss it most. Nearly 3 in 4 adults under 40 with high blood pressure don’t know they have it.
  • They’re easy to find. A blood pressure check and a routine blood test cover almost everything on this page.
Who doesn’t know they have it
Share of US adults with each condition who don’t know they have it
Chronic kidney disease37M adults (14%)
Prediabetes115.2M adults (more than 2 in 5)
High blood pressure47.7% of adults
Diabetes40.1M people
↓ Data (CSV) Cite

Sources: CDC National Diabetes Statistics Report (2026), CDC Chronic Kidney Disease in the United States (2026), NCHS Data Brief No. 511 (2024). Kidney disease awareness is for adults 20 and older.

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Picture a room of 10 adults

Percentages can feel abstract. Here’s what the numbers look like in a room of 10 US adults.

In a room of 10 US adults
Roughly how many have each condition. Filled figures have it.
High blood pressure About 5 in 10 Prediabetes More than 4 in 10 Kidney disease More than 1 in 10 Diabetes About 1 in 8

Rounded from CDC figures: high blood pressure 47.7% of adults, prediabetes more than 2 in 5 adults, kidney disease 14% of adults and diabetes 12.0% of people. One person can have more than one condition, so the rows overlap.

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Put another way: chances are someone you know is living with one of these right now, and may not know it yet.

Why so many people don’t know

These conditions have something in common. In the early years, most of them don’t hurt, don’t make you tired and don’t change how you feel. You can feel completely fine while your blood sugar, blood pressure or kidney function slowly drifts in the wrong direction.

Think of it like this

It’s like a slow leak in a tire. The car drives fine for weeks, and nothing feels different from the driver’s seat. A tire gauge spots the leak in seconds, long before you’d ever notice it on the road. A blood pressure cuff and a routine blood test are the tire gauge.

Three things people often think

What people think“I’d feel it if something was wrong.”
What the data saysEarly on, most of these cause no symptoms. About 9 in 10 people with kidney disease don’t know they have it.
What people think“I’m too young to worry about this.”
What the data saysAlmost 1 in 4 adults under 40 has high blood pressure, and most of them don’t know.
What people think“My numbers were fine a few years ago.”
What the data saysThese numbers drift slowly. That’s why guidelines say to check blood pressure every year from age 40.
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The conditions, one by one

Prediabetes

Your blood sugar is higher than normal, but not high enough to be called diabetes yet. It’s common, it’s quiet, and it’s often reversible with changes to diet, activity and weight.

115.2Madults have it
More than 2 in 5US adults
8 in 10don’t know it

Of every 10 adults with prediabetes, 8 don’t know it (outlined) and 2 do (filled).

It gets more common with age. More than half of adults 65 and older (52.1%, or 31.3 million people) have prediabetes. The CDC says healthy changes, like losing a modest amount of weight and moving more, can cut the risk of type 2 diabetes in half.

Higher risk if you: have overweight or obesity, are 45 or older, have a parent or sibling with type 2 diabetes, are active less than 3 times a week or had diabetes during pregnancy.

How it’s found: an A1c or fasting glucose blood test. Both are in our biomarker guide.

Chronic kidney disease

The kidneys slowly lose their ability to filter blood. Early on there’s usually nothing to feel, which is why it’s the least-known condition on this list.

37Madults have it
14%of US adults
9 in 10don’t know it

Higher risk if you: have diabetes or high blood pressure (the two biggest causes), have heart disease, have obesity or have family members with kidney disease. About 1 in 5 adults with high blood pressure has kidney disease.

How it’s found: a blood test for kidney function (eGFR, from creatinine) and a urine test for protein (the albumin-to-creatinine ratio).

High blood pressure

The force of blood against your artery walls stays too high. Over years it strains the heart, brain, kidneys and eyes. It’s the most common condition on this list.

47.7%of US adults have it
About 4 in 10of them don’t know it
About 1 in 5of them have it under control

Gets more common with age: about 23% of adults under 40, 53% of adults 40 to 59 and 72% of adults 60 and older.

How it’s found: a blood pressure check. It takes about a minute, and many pharmacies have a free machine.

Diabetes

Blood sugar stays high enough to damage blood vessels and nerves over time. Most adults with diabetes know it, but a large group still doesn’t.

40.1Mpeople have it
11.0Maren’t diagnosed
About 3 in 10adults with it don’t know it

Higher risk if you: have the same risk factors as prediabetes. Having prediabetes is a major warning sign.

How it’s found: the same A1c or fasting glucose test used for prediabetes.

High cholesterol

Too much cholesterol in the blood builds up in artery walls over time. There are no symptoms at all, so the only way to know is a test.

11.3%of adults have high total cholesterol
16.7%of adults 40 to 59
How it’s found: a lipid panel, a routine blood test. The CDC doesn’t publish an “unaware” number for cholesterol, so it isn’t in the chart above.

Younger adults are the least likely to know

High blood pressure isn’t just an older person’s problem. Almost 1 in 4 adults under 40 has it, and nearly 3 in 4 of them don’t know.

Adults with high blood pressure who don’t know it, by age
Share unaware, 2021 to 2023
18 to 3923.4% have it
40 to 5952.5% have it
60 and older71.6% have it

Source: NCHS Data Brief No. 511. High blood pressure here means 130/80 or higher, or taking blood pressure medicine.

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One often leads to another

These conditions don’t stay in their own lanes. Catching one early can help you head off the next.

PrediabetesBlood sugar creeping up
Type 2 diabetesIf nothing changes
Kidney diseaseDiabetes and high blood pressure are its two biggest causes

High blood pressure feeds into the same chain. About 1 in 5 adults with high blood pressure already has kidney disease.

When to get checked

Here’s what US screening guidelines say for adults without symptoms. Your doctor may suggest more, based on your history.

TestWhat it findsHow often
Blood pressure checkHigh blood pressureEvery year from age 40, or if you’re at higher risk. Every 3 to 5 years from 18 to 39 if your last reading was normal.
A1c or fasting glucosePrediabetes and diabetesAdults 35 to 70 with overweight or obesity. About every 3 years if normal.
Kidney blood and urine testsKidney diseaseAsk your doctor, especially if you have diabetes or high blood pressure.
Lipid panelHigh cholesterolAsk your doctor. Many adults get it with routine blood work.

Source: US Preventive Services Task Force (blood pressure, 2021; prediabetes and diabetes, 2021). Kidney and cholesterol timing depends on your health, so it’s a conversation with your doctor.

What you can do about it

The good news: every condition on this page can be found with quick, common tests, and most are part of a routine checkup. Start with your regular doctor. A yearly checkup with a blood pressure check and routine blood work catches most of this.

Longevity care can add to that, with a wider blood panel, more frequent tracking and a plan to keep the numbers moving the right way. If you’re curious what that looks like, read biomarker testing vs. your annual physical or see clinics near you.

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LongevityClinicsHub. (2026, October). How many Americans have a health problem and don’t know it? https://longevityclinicshub.com/learn/undiagnosed-health-conditions/ (Data: CDC.)

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Common questions

How many Americans have prediabetes?

115.2 million US adults, which is more than 2 in 5. 8 in 10 of them don’t know they have it.

What percentage of people with kidney disease don’t know it?

About 9 in 10 (87%) adults 20 and older with chronic kidney disease don’t know they have it, according to the CDC.

How many people have undiagnosed diabetes?

About 11.0 million, or 27.6% of adults with diabetes.

How many adults with high blood pressure don’t know it?

About 4 in 10. In 2021 to 2023, 59.2% of adults with high blood pressure had been told they have it. Among adults under 40, only 27.2% knew.

How often should I get my blood pressure checked?

US guidelines say every year from age 40, or if you’re at higher risk. Adults 18 to 39 with a normal reading can check every 3 to 5 years.

Can you have these conditions without symptoms?

Yes. That’s why they go unnoticed. Prediabetes, early kidney disease, high blood pressure and high cholesterol usually cause no symptoms for years. A blood pressure check and routine blood tests are how they’re found.

Prepared by the LongevityClinicsHub editorial team. How we research and source these guides.

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Sources

This guide is independent editorial content, written to orient, not to diagnose. It is not medical advice, and it is no substitute for a conversation with a licensed physician who knows your history. Where we describe what clinics claim, the claim belongs to the clinic.

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